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Hidevaldo Machado
Hidevaldo Machado
GE Healthcare
Molecular biology
Biology
Genome editing
CRISPR
Trans-activating crRNA
4
Papers
101
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DEVELOPMENT OF A NEXT GENERATION ALLOGENEIC CAR-T CELL PLATFORM WITHOUT GENE EDITING: PS1210
2019
Panagiota A. Sotiropoulou
Alexandre Michaux
Susanna Raitano
Simon Bornschein
Jennifer Bolsée
Steve Lenger
Hidevaldo Machado
J.D. Moore
David E. Gilham
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Next Generation NKG2D-based CAR T-cells (CYAD-02): Co-expression of a Single shRNA Targeting MICA and MICB Improves Cell Persistence and Anti-Tumor Efficacy in vivo
2019
Blood
Martina Fontaine
Benjamin Demoulin
Simon Bornschein
Susanna Raitano
Steve Lenger
Hidevaldo Machado
Jonathan D. Moore
Panagiota A. Sotiropoulou
David E. Gilham
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Citations (2)
Systematic analysis of CRISPR-Cas9 mismatch tolerance reveals low levels of off-target activity.
2015
Journal of Biotechnology
Emily Anderson
Amanda Haupt
John A. Schiel
Eldon T. Chou
Hidevaldo Machado
Žaklina Strezoska
Steve Lenger
Shawn McClelland
Amanda Birmingham
Annaleen Vermeulen
Anja van Brabant Smith
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Citations (99)
Increasing gene editing efficiencies in eukaryotic cell lines by selection of appropriate CRISPR-Cas9 reagents
2015
Cytotherapy
Melissa L. Kelley
Žaklina Strezoska
Hidevaldo Machado
Emily Anderson
Maren Mayer
Annaleen Vermeulen
Shawn McClelland
Anja van Brabant Smith
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