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Sarah E. Sinnett

University of North Carolina at Chapel Hill

11

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149

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Engineered microRNA-based regulatory element permits safe high-dose miniMECP2 gene therapy in Rett mice

2021 Brain
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Intellectual and Developmental Disabilities Research Centers: A Multidisciplinary Approach to Understand the Pathogenesis of Methyl-CpG Binding Protein 2-related Disorders.

2020 Neuroscience
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Recent endeavors in MECP2 gene transfer for gene therapy of Rett Syndrome

2017 Discovery Medicine
- Sarah E. Sinnett
- Steven James Gray
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Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery

2017 Molecular therapy. Methods & clinical development
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Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett Syndrome

2017 Molecular therapy. Methods & clinical development
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713. IntraCSF Administration of AAV9/MeCP2 Extends Lifespan of MeCP2-Null Mice While Preventing Toxicity Associated With IV Administration

2015 Molecular Therapy
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A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK)

2013 Current Chemical Genomics
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Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats.

2011 Psychopharmacology
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Citations (22)