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Igor Baburin

University of Vienna

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Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo

2018 Pharmacological Research
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Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

2017 Cell
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Comparison of HERG ion channel effects in HEK cells and action potential duration in human iPSC cardiomyocytes

2016 Journal of Pharmacological and Toxicological Methods
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On the Relation between HERG Channel Block in Cell Line and Action Potential Prolongation in Human iPSC Cardiomyocytes

2016 Biophysical Journal
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Nitrogenated honokiol derivatives allosterically modulate GABAA receptors and act as strong partial agonists

2015 Bioorganic & Medicinal Chemistry
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Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives.

2014 Journal of Medicinal Chemistry
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The 'Lotus Leave Diet' – A life-threatening experience? hERG channel blocking aporphine alkaloids from Nelumbo nucifera Gaertn

2014 Planta Medica
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DEHYDROEVODIAMINE, ISOLATED FROM THE DRIED UNRIPE FRUIT OF EVODIA RUTAECARPA PRESENT IN THE TRADITIONAL CHINESE MEDICINE WU CHU YU, HAS PROARRHYTHMIC EFFECTS IN VITRO AND IN VIVO THAT DISAPPEAR AT HIGHER CONCENTRATIONS

2014 Heart Rhythm
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Natural products as potential human ether-a-go-go-related gene channel inhibitors - screening of plant-derived alkaloids.

2014 Planta Medica
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HERG PHARMACOPHORE MODELS AS CARDIAC TOXICITY PREDICTION TOOLS: IDENTIFICATION OF CHANNEL BLOCKERS OF NATURAL ORIGIN

2014 Vitae-revista De La Facultad De Quimica Farmaceutica
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