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Jacob D. Aguirre

University of Western Ontario

9

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343

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Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.

2018 The EMBO Journal
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Synergistic Recruitment of UbcH7~Ub and Phosphorylated Ubl Domain Triggers Parkin Activation

2018 bioRxiv
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UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin

2018
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Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation

2017 Proceedings of the National Academy of Sciences of the United States of America
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Solution structure of Serine 65 phosphorylated UBL domain from parkin

2016 Journal of Back and Musculoskeletal Rehabilitation
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Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping

2016 FEBS Letters
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Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

2015 The EMBO Journal
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A molecular explanation for the recessive nature of parkin -linked Parkinson’s disease

2013 Nature Communications
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Citations (113)