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Does large NGS panel analysed using exome tumour sequencing improve the management of advanced non-small-cell lung cancers?

2021 Lung Cancer
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The tumor microenvironment impairs Th1 IFNγ secretion through alternative splicing modifications of Irf1 pre-mRNA.

2021 Cancer immunology research
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An Algorithm Combining Patient Performance Status, Second Hit Analysis, PROVEAN and Dann Prediction Tools Could Foretell Sensitization to PARP Inhibitors in Digestive, Skin, Ovarian and Breast Cancers

2021 Cancers
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PARP inhibitor resistance and TP53 mutations in patients treated with olaparib for BRCA-mutated cancer: Four case reports

2020 Molecular Medicine Reports
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Prediction of olaparib sensitivity for variants of unknown significance in homologous repair genes.

2019 Journal of Clinical Oncology
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P1.14-19 Exome Analysis of Patients Treated with Afatinib Reveals Genetic Variations Discriminating Extreme Responders

2019 Journal of Thoracic Oncology
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Cleaved Caspase-3 transcriptionally regulates angiogenesis promoting chemotherapy resistance

2019 Cancer Research
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Exome analysis to reveal genomic markers associated with better efficacy of nivolumab in lung cancer patients.

2018 Journal of Clinical Oncology
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Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

2018 Nature Communications
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Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy

2018 British Journal of Cancer
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