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Bruce R. Conklin

University of California, San Francisco
Gladstone Institutes

202

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16183

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BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2

2021 bioRxiv
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SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.

2021 Science Translational Medicine
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Functional analysis of a common BAG3 allele associated with protection from heart failure

2021 bioRxiv
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Allele-specific gene editing rescues pathology in a human model of Charcot-Marie-Tooth disease type 2E

2021 bioRxiv
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Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies.

2021 Nature Communications
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Bioengineered optogenetic model of human neuromuscular junction.

2021 Biomaterials
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Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells.

2020 Cell Reports
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Integration of Protein Interactome Networks With Congenital Heart Disease Variants Reveals Candidate Disease Genes

2020
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Laboratory heart model for drug screening

2020
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Silencing of E-cadherin in induced human pluripotent stem cells promotes extraembryonic fates accompanying multilineage differentiation

2020 bioRxiv
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