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Morvarid Mohseni

Novartis

38

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Author response: Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling

2021 eLife
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Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling.

2021 eLife
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Combinations with allosteric SHP2 inhibitor TNO155 to block receptor tyrosine kinase signaling.

2020 Clinical Cancer Research
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Abstract A44: SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS-mutant tumors treated with MEK inhibitors

2020 Molecular Cancer Research
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Abstract LB-122: Combinations of SHP2 inhibitor to overcome RAS activation by receptor tyrosine kinases in response to ERK inhibition

2020
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Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling

2019 bioRxiv
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Abstract 954: SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS mutant tumors treated with MEK inhibitors

2019 Cancer Research
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Tumor intrinsic efficacy by SHP2 and RTK inhibitors in KRAS mutant cancers.

2019 Molecular Cancer Therapeutics
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6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

2019 Journal of Medicinal Chemistry
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Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates

2018 ACS Medicinal Chemistry Letters
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