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Shuo Gu

Stanford University

18

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1110

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Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires

2019 Cell Reports
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IsomiRs: Expanding the miRNA repression toolbox beyond the seed

2019 Biochimica et Biophysica Acta
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737. RNAi Induced Hepatotoxicity Results from a Functional Depletion of the First Synthesized Isoform of miR-122

2016 Molecular Therapy
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154. Applying Insights from Pri-miRNA Processing to shRNA Design

2016 Molecular Therapy
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Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain

2012 Current Biology
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The loop position of shRNAs and pre-miRNAs is critical for the accuracy of Dicer processing in vivo

2012 Cell
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Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

2010 Journal of Clinical Investigation
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Functional and intracellular localization properties of U6 promoter-expressed siRNAs, shRNAs, and chimeric VA1 shRNAs in mammalian cells.

2008 RNA
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Inhibition of infectious human immunodeficiency virus type 1 virions via lentiviral vector encoded short antisense RNAs.

2006 Oligonucleotides
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Citations (15)