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Juraj Kóňa

Slovak Academy of Sciences

17

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288

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Synthesis of hydroxymethyl analogues of mannostatin A and their evaluation as inhibitors of GH38 α-mannosidases

2021 New Journal of Chemistry
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Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group

2021 New Journal of Chemistry
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Synthesis of N-benzyl substituted 1,4-imino-l-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb

2019 Bioorganic Chemistry
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Medicinal chemistry: an effect of a desolvation penalty of an amide group in the development of kinase inhibitors

2019 Chemical Papers
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Using DFT methodology for more reliable predictive models: Design of inhibitors of Golgi α-Mannosidase II.

2016 Journal of Molecular Graphics & Modelling
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'Click chemistry' synthesis of 1-(α-D-mannopyranosyl)-1,2,3-triazoles for inhibition of α-mannosidases.

2015 Carbohydrate Research
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Theoretical study of enzymatic catalysis explains why the trapped covalent intermediate in the E303C mutant of glycosyltransferase GTB was not detected in the wild-type enzyme

2015 Glycobiology
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A theoretical study on the catalytic mechanism of the retaining α-1,2-mannosyltransferase Kre2p/Mnt1p: the impact of different metal ions on catalysis

2014 Organic and Biomolecular Chemistry
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Cover Picture: Structure–Activity Relationships of Glycogen Phosphorylase Inhibitor FR258900 and Its Analogues: A Combined Synthetic, Enzyme Kinetics, and Computational Study (ChemPlusChem 11/2014)

2014 ChemPlusChem
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PEGylated Nanoparticles Bind to and Alter Amyloid-Beta Peptide Conformation: Toward Engineering of Functional Nanomedicines for Alzheimer’s Disease

2012 ACS Nano
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