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Jamie B. Miyamoto

Seattle Genetics

18

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1103

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Novel Auristatins with High Bystander and Cytotoxic Activities in Drug-Efflux Positive Tumor Models

2020 Molecular Cancer Therapeutics
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Orthogonal Cysteine Protection Enables Homogeneous Multi‐Drug Antibody–Drug Conjugates

2017 Angewandte Chemie
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The Methylene Alkoxy Carbamate Self-Immolative Unit: Utilization for the Targeted Delivery of Alcohol-Containing Payloads with Antibody-Drug Conjugates.

2016 Angewandte Chemie
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SGN–LIV1A: A Novel Antibody–Drug Conjugate Targeting LIV-1 for the Treatment of Metastatic Breast Cancer

2014 Molecular Cancer Therapeutics
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Abstract 3962: SGN-LIV1A: a development stage antibody drug-conjugate targeting LIV-1 for the treatment of metastatic breast cancer.

2013 Cancer Research
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Abstract 1789: Auristatin-based antibody-drug conjugates are synergistic in combination with PI3K-AKT-mTOR pathway inhibitors in hematologic malignancies and carcinoma

2011 Cancer Research
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Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate

2010 Clinical Cancer Research
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Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.

2009 mAbs
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Design, Synthesis, and Biological Evaluation of Antibody-Drug Conjugates Comprised of Potent Camptothecin Analogues

2009 Bioconjugate Chemistry
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Novel Peptide Linkers for Highly Potent Antibody−Auristatin Conjugate

2008 Bioconjugate Chemistry
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Citations (121)