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Sachin Thigale
Sachin Thigale
Novartis
Biology
Biochemistry
Combinatorial chemistry
Enzyme
Nicotinamide phosphoribosyltransferase
4
Papers
58
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Scaffold morphing identifies 3-pyridyl azetidine ureas as inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)
2019
ACS Medicinal Chemistry Letters
Daniel S. Palacios
Erik Meredith
Toshio Kawanami
Christopher M. Adams
Xin Chen
Veronique Darsigny
Mark G. Palermo
Daniel Baird
Elizabeth George
Chantale T. Guy
Jeffrey Hewett
Laryssa Tierney
Sachin Thigale
Louis Wang
Wilhelm A. Weihofen
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Structure based design of Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen
2017
Bioorganic & Medicinal Chemistry Letters
Daniel S. Palacios
Erik Meredith
Toshio Kawanami
Christopher M. Adams
Xin Chen
Veronique Darsigny
Erin Geno
Mark G. Palermo
Daniel Baird
Geoffrey Boynton
Scott A. Busby
Elizabeth L. George
Chantale T. Guy
Jeffrey Hewett
Laryssa Tierney
Sachin Thigale
Wilhelm Weihofen
Louis Wang
Nicole White
Ming Yin
Upendra A. Argikar
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A systematic comparison of enzymatic activity and protein interaction analysis of the KDM3 histone demethylase subfamily.
2013
Michael Brauchle
Zhiping Yao
Rishi Arora
Ieuan Clay
Bruno Inverardi
Bertran Gerrits
Johannes Voshol
Andreas Bauer
Dirk Schuebeler
Antonius Bouwmeester
Heinz Ruffner
Sachin Thigale
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Protein Complex Interactor Analysis and Differential Activity of KDM3 Subfamily Members Towards H3K9 Methylation
2013
PLOS ONE
Michael Brauchle
Zhiping Yao
Rishi Arora
Sachin Thigale
Ieuan Clay
Bruno Inverardi
Joy Fletcher
Paul Taslimi
Michael G. Acker
Bertran Gerrits
Johannes Voshol
Andreas Bauer
Dirk Schübeler
Tewis Bouwmeester
Heinz Ruffner
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