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Nigel J. Waterhouse

Peter MacCallum Cancer Centre

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The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress

2014 Cell Death & Differentiation
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Visualizing CTL activity for different CD8(+) effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing

2009 Cell Death & Differentiation
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Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules.

2008 Methods
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Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity

2008 Cell Death & Differentiation
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H is for helper: granzyme H helps granzyme B kill adenovirus-infected cells

2007 Trends in Immunology
- Nigel J. Waterhouse
- Joseph A. Trapani
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Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.

2007 Journal of Cell Biology
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Residual active granzyme B in cathepsin C–null lymphocytes is sufficient for perforin-dependent target cell apoptosis

2007 Journal of Experimental Medicine
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GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

2007 Cell
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A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance

2007 Cell Death & Differentiation
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Functional dissociation of ΔΨm and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis

2006 Cell Death & Differentiation
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