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Masayuki Gotoh

Takeda Pharmaceutical Company

7

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Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐b]Pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 2

2019 ChemMedChem
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Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-based p38 MAP Kinase Inhibitors: Part 1.

2019 ChemMedChem
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Gene Signature–Based Approach Identified MEK1/2 as a Potential Target Associated With Relapse After Anti-TNFα Treatment for Crohn’s Disease

2018 Inflammatory Bowel Diseases
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αvβ3 Integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes

2006 Journal of Bone and Mineral Metabolism
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Enhancement of osteogenesis in vitro by a novel osteoblast differentiation-promoting compound, TAK-778, partly through the expression of Msx2.

2002 European Journal of Pharmacology
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Enhancement of Osteogenesis In Vitro and In Vivo by a Novel Osteoblast Differentiation Promoting Compound, TAK-778

1999 Journal of Pharmacology and Experimental Therapeutics
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Synthesis of novel 2-benzothiopyran and 3-benzothiepin derivatives and their stimulatory effect on bone formation.

1999 Journal of Medicinal Chemistry
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