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Pearl Huang
Pearl Huang
GlaxoSmithKline
Biology
Cancer research
Cancer
Mitosis
Cell biology
5
Papers
69
Citations
0.01
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A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A), demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro
2007
Molecular Cancer Therapeutics
David Sutton
Aidan G. Gilmartin
Anna Kusnierz
Chiu-Mei Sung
Lusong Luo
Jeffrey D. Carson
Sylvie Laquerre
William D. Cornwell
Andrew G. King
Steven D. Knight
Dashyant Dhanak
Gustave Bergnes
Xiangping Qian
Penelope Chua
Kenneth W. Wood
Pearl Huang
Barbara L. Weber
Robert A. Copeland
Jeffrey R. Jackson
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Citations (7)
A second generation KSP inhibitor, SB-743921, is a highly potent and active therapeutic in preclinical models of cancer
2006
Clinical Cancer Research
Jeffrey R. Jackson
Aidan G. Gilmartin
Dash Dhanak
Steven D. Knight
Cindy Parrish
Lusong Luo
David Sutton
Eian Caulder
Melody Diamond
Michele Giardiniere
Shuyun Zhang
Pearl Huang
Gustave Bergnes
Andrew Mcdonald
Yan Lee
Roman Sakowicz
Kenneth W. Wood
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Citations (8)
A method for determining intracellular concentrations of enzyme substrates from a combination of competitive inhibition and mutagenesis studies
2005
Analytical Biochemistry
Robert A. Copeland
Lusong Luo
Kurt R. Auger
Pearl Huang
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Citations (2)
A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis.
2002
Current Opinion in Chemical Biology
Jerry L. Adams
Pearl Huang
Denis R. Patrick
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Citations (48)
1