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Michael Webb

Johnson & Johnson Pharmaceutical Research and Development

12

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516

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The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors.

2016 Bioorganic & Medicinal Chemistry Letters
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Preclinical Characterization of the FAAH Inhibitor JNJ-42165279

2015 ACS Medicinal Chemistry Letters
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1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.

2014 Bioorganic & Medicinal Chemistry Letters
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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

2012 Bioorganic & Medicinal Chemistry Letters
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Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate

2012 ACS Medicinal Chemistry Letters
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Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

2009 British Journal of Pharmacology
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Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

2009 Anesthesia & Analgesia
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Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH).

2008 Bioorganic & Medicinal Chemistry Letters
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Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase

2008 Bioorganic & Medicinal Chemistry Letters
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Citations (73)