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Joachim Clos

Bernhard Nocht Institute for Tropical Medicine

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Life Cycle Stage-Specific Accessibility of Leishmania donovani Chromatin at Transcription Start Regions.

2021
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Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival.

2021 Frontiers in Cellular and Infection Microbiology
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The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity

2020 bioRxiv
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Heat Shock Proteins in Leishmania Parasites

2020
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Anti-leishmanial effects of synthetic EhPIb analogs derived from the Entamoeba histolytica lipopeptidephosphoglycan.

2020 Antimicrobial Agents and Chemotherapy
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Application of CRISPR/Cas9-Based Reverse Genetics in Leishmania braziliensis: Conserved Roles for HSP100 and HSP23.

2020 Genes
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Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

2019
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Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics

2019 European Journal of Medicinal Chemistry
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Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in Leishmania donovani

2018
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Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent

2018
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