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Meifang Wang

University of Pittsburgh

29

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871

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Abstract 5407: Inhibitory Raf-1 phosphorylations at Ser-43 and Ser-259 are induced in vitamin K1 enhancement of Sorafenib-mediated HCC cell growth inhibition

2010 Cancer Research
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HKH40A (RTA 502) inhibits growth of hepatocellular carcinoma cells both in vitro and in vivo by arresting cells in G2/M phase of the cell cycle via Cdc25C phosphorylation and inducing apoptosis

2007 Cancer Research
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α-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis

2007 Molecular and Cellular Biochemistry
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H32, a new non-quinone vitamin K sulfone analog, inhibits tumor cell growth by MAPK activation

2006 Cancer Research
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PM-20, a novel inhibitor of Cdc25A, induces extracellular signal–regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo

2006 Molecular Cancer Therapeutics
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Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK.

2006 Biochemical Pharmacology
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H32, a non-quinone sulfone analog of vitamin K3, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating ERK.

2006 Cancer Biology & Therapy
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Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.

2005 Molecular Cancer Therapeutics
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Involvement of c-Myc in growth inhibition of Hep 3B human hepatoma cells by a vitamin K analog

2004 Journal of Hepatology
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Inhibition of rat liver regeneration after partial hepatectomy and induction of ERK phosphorylation by Cpd 5, a K vitamin-based anticancer compound

2004 Carcinogenesis
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