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Kevin Drenner

University of California, San Diego

11

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1312

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Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration

2019 Nature Neuroscience
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Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis

2017 Acta Neuropathologica
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Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

2016 The EMBO Journal
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Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

2016 Neuron
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Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.

2013 Proceedings of the National Academy of Sciences of the United States of America
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