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Carla T. Helaszek

13

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Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin‐l β converting enzyme (ICE)

2009 International Journal of Peptide and Protein Research
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3-chloro-4-carboxamido-6-arylpyridazines as a non-peptide class of interleukin-1β converting enzyme inhibitor

1997 Bioorganic & Medicinal Chemistry Letters
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Pyridazinodiazepines as a High-Affinity, P2−P3 Peptidomimetic Class of Interleukin-1β-Converting Enzyme Inhibitor

1997 Journal of Medicinal Chemistry
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First examples of peptidomimetic inhibitors of interleukin-1β converting enzyme

1996 Journal of Medicinal Chemistry
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Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme (ICE)

1995 Bioorganic & Medicinal Chemistry Letters
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Secretion of human monocyte mature IL-1β: Optimization of culture conditions and inhibition by ICE inhibitors

1995 Inflammation Research
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Aspartyl .alpha.-((Diphenylphosphinyl)oxy)methyl Ketones as Novel Inhibitors of Interleukin-1.beta. Converting Enzyme. Utility of the Diphenylphosphinic Acid Leaving Group for the Inhibition of Cysteine Proteases

1995 Journal of Medicinal Chemistry
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Structural and stereochemical requirements of time-dependent inactivators of the interleukin-1β converting enzyme

1995 Bioorganic & Medicinal Chemistry Letters
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P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme.

1994 Journal of Medicinal Chemistry
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Production of active human interleukin-1β-converting enzyme in a baculovirus expression system

1994 Gene
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Citations (11)