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Jason Pickens
Jason Pickens
Takeda Pharmaceutical Company
Kinase
Protein Data Bank
Lead compound
Biochemistry
ASK1
2
Papers
12
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0
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Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis
2020
Emma L. Shepherd
Raquel Saborano
Ellie Northall
Kae Matsuda
Hitomi Ogino
Hiroaki Yashiro
Jason Pickens
Ryan E. Feaver
Banumathi K. Cole
Stephen A. Hoang
Mark J. Lawson
Matthew Olson
Robert A. Figler
John E. Reardon
Nobuhiro Nishigaki
Brian R. Wamhoff
Ulrich L. Günther
G.M. Hirschfield
Derek M. Erion
Patricia F. Lalor
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Citations (9)
Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile
2020
Bioorganic & Medicinal Chemistry Letters
Simone V. Bigi-Botterill
Anthony Ivetac
Erica L. Bradshaw
Derek Cole
Douglas R. Dougan
Jacques Ermolieff
Petro Halkowycz
Ben Johnson
Christopher Mcbride
Jason Pickens
Mark Sabat
Steven Swann
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Citations (3)
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