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Randell T. Libby

University of Washington

18

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2695

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Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age

2014 Human Molecular Genetics
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CTCF Regulates Ataxin-7 Expression through Promotion of a Convergently Transcribed, Antisense Noncoding RNA

2011 Neuron
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CTCF cis-Regulates Trinucleotide Repeat Instability in an Epigenetic Manner: A Novel Basis for Mutational Hot Spot Determination

2008 PLOS Genetics
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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration

2006 Cell Metabolism
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Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport

2006 Nature Neuroscience
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Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

2004 Neuron
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Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice

2003 Human Molecular Genetics
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Polyglutamine-Expanded Ataxin-7 Promotes Non-Cell-Autonomous Purkinje Cell Degeneration and Displays Proteolytic Cleavage in Ataxic Transgenic Mice

2002 The Journal of Neuroscience
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Molecular Modeling and Preclinical Evaluation of the Humanized NR-LU-13 Antibody

1999 Clinical Cancer Research
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Phosphorolytic error correction during transcription

1994 Molecular Microbiology
- Randell T. Libby
- Jonathan Gallant
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Citations (7)