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John D. Prugh

United States Military Academy

14

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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors.

2000 Bioorganic & Medicinal Chemistry Letters
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Nonpeptide GPIIb/IIIa Inhibitors. Part 16. Thieno(2,3-b)thiophene . alpha.-Sulfonamides are Potent Inhibitors of Platelet Aggregation.

1997 ChemInform
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Nonpeptide GPIIB/IIIA inhibitors. 16. Thieno[2,3-b]thiophene α-sulfonamides are potent inhibitors of platelet aggregation

1997 Bioorganic & Medicinal Chemistry Letters
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A Simple Method of Protecting a Secondary Amine with tert‐ Butyloxycarbonyl (Boc) in the Presence of a Primary Amine.

1993 ChemInform
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A Simple Method of Protecting a Secondary Amine with Tert Butyloxycarbonyl (Boc) in the Presence of a Primary Amine

1992 Synthetic Communications
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New Isomeric Classes of Topically Active Ocular Hypotensive Carbonic Anhydrase Inhibitors: 5-Substituted Thieno(2,3-b)thiophene-2-sulfonamides and 5-Substituted Thieno(3,2-b)thiophene-2-sulfonamides.

1991 ChemInform
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New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

1991 Journal of Medicinal Chemistry
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3‐Hydroxy‐3‐methylglutarylcoenzyme A Reductase Inhibitors. Part 6. trans‐6‐(2‐(Substituted‐1‐Naphthyl)ethyl(or ethenyl))‐3,4,5,6‐tetrahydro‐4‐hydroxy‐2H‐pyran‐2‐ones.

1990 ChemInform
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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. Trans-6-[2-(substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones.

1990 Journal of Medicinal Chemistry
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A Convenient Synthesis of 5‐Substituted‐4‐Hydroxy‐3,4,5,6‐tetrahydro‐2H‐pyran‐2‐ones via a Chemoselective Differentiation of the Two Ester Functions of Dimethyl Acetonedicarboxylate.

1988 ChemInform
- John D. Prugh
- A. A. Deana
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