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Zhen Chen

Harvard University

50

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Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold.

2021 Journal of Medicinal Chemistry
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Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping

2021 Acta Pharmaceutica Sinica B
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[18F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

2021 Acta Pharmaceutica Sinica B
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[18F]- Alfatide PET imaging of integrin αvβ3 for the non-invasive quantification of liver fibrosis

2020 Journal of Hepatology
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Radiosynthesis and preliminary evaluation of 11C-labeled 4-cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-benzo[e] [1,2,4] thiadiazine 1,1-dioxide for PET imaging AMPA receptors

2020 Tetrahedron Letters
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Synthesis and Pharmacokinetic Study of a 11C-Labeled Cholesterol 24-Hydroxylase Inhibitor Using ‘In-Loop’ [11C]CO2 Fixation Method

2020 ChemRxiv
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Synthesis and preliminary evaluation of novel 11 C-labeled GluN2B-selective NMDA receptor negative allosteric modulators

2020 Acta Pharmacologica Sinica
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Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET

2020 Bioorganic & Medicinal Chemistry Letters
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Synthesis and pharmacokinetic study of a 11C-labeled cholesterol 24-hydroxylase inhibitor using ‘in-loop’ [11C]CO2 fixation method

2020 Bioorganic & Medicinal Chemistry Letters
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Radiosynthesis of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one as a novel PET tracer towards imaging of γ-8 dependent transmembrane AMPA receptor regulatory protein

2020 The Journal of Nuclear Medicine
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