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Youhei Sohma

Kyoto Pharmaceutical University
University of Tokyo

121

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Development of Artificial Catalysts that Photooxygenate Pathogenic Amyloid

2021
- Youhei Sohma
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Catalytic photooxygenation degrades brain Aβ in vivo.

2021 Science Advances
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Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer's disease mice.

2021 Brain
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Chemical Catalyst‐Mediated Selective Photo‐oxygenation of Pathogenic Amyloids

2020
- Youhei Sohma
- Motomu Kanai
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Design and properties of [Met35(O)]Aβ42-lactam(Asp23/Lys28) possessing a lactam tether as a salt-bridge surrogate

2019 Bioorganic & Medicinal Chemistry
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Development of Artificial Catalysts that Selectively Photooxygenate Pathogenic Amyloid

2019 Journal of Synthetic Organic Chemistry Japan
- Youhei Sohma
- Motomu Kanai
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Design, synthesis, and properties of a chemically-tethered amyloid-β segment trimer resistant to inter-trimer mis-aggregation

2019 Journal of Organic Chemistry
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PHOTOOXYGENATION BY BIOCOMPATIBLE CATALYST REDUCES THE Aβ LEVEL IN THE BRAINS OF ALZHEIMER DISEASE MODEL MICE

2019 Alzheimers & Dementia
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Photo-oxygenation inhibits tau amyloid formation

2019 Chemical Communications
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Hydroxy Group Directed Catalytic Hydrosilylation of Amides

2018 Organic Letters
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