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John Schindler

University of Texas Southwestern Medical Center

41

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Immunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity

2012 mAbs
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Synergy of sequential administration of a deglycosylated ricin A chain-containing combined anti-CD19 and anti-CD22 immunotoxin (Combotox) and cytarabine in a murine model of advanced acute lymphoblastic leukemia.

2012 Leukemia & Lymphoma
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Pilot Phase IB Clinical Trial of an Alhydrogel-Adsorbed Recombinant Ricin Vaccine

2012 Clinical and Vaccine Immunology
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A phase I study of a combination of anti-CD19 and anti-CD22 immunotoxins (Combotox) in adult patients with refractory B-lineage acute lymphoblastic leukaemia.

2011 British Journal of Haematology
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immunotoxin, IgG-HD37-dgA, in patients with B-cell lymphoma A phase I study of bolus versus continuous infusion of the anti-CD19

2011
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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

2011 The New England Journal of Medicine
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CASPALLO: Phase I Clinical Trial of Allodepleted T Cells Transduced with Inducible Caspase 9 Suicide Gene After Haploidentical Stem Cell Transplantation

2010 Blood
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A Phase 1 Study of Combotox in Pediatric Patients With Refractory B-lineage Acute Lymphoblastic Leukemia

2009 Journal of Pediatric Hematology Oncology
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Partial Reduction of Human FOXP3+ CD4 T Cells In Vivo After CD25-directed Recombinant Immunotoxin Administration

2008 Journal of Immunotherapy
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Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease

2007 Blood
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