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Attila A. Seyhan

Brown University

8

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170

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EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG.

2021 Neoplasia
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Abstract 1156: The integrated stress response (ISR) is involved in the synergistic combinatorial efficacy of ONC201 and epigenetic modulators in brain tumor cell lines

2021 Cancer Research
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Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells

2020 bioRxiv
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Are innovation and new technologies in precision medicine paving a new era in patients centric care

2019 Journal of Translational Medicine
- Attila A. Seyhan
- Claudio Carini
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Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

2019
- Attila A. Seyhan
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Citations (79)