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Nicholas I. Brodie

University of Victoria

11

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231

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Ligand-induced disorder-to-order transitions characterized by structural proteomics and molecular dynamics simulations

2020 Journal of Proteomics
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The structure of the native α-synuclein ensemble determined using a combination of structural proteomics and discrete molecular dynamics simulations

2020
- Nicholas I. Brodie
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Conformational ensemble of native α-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations

2019 PLOS Computational Biology
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MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

2019 Epigenetics & Chromatin
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Top-Down Hydrogen–Deuterium Exchange Analysis of Protein Structures Using Ultraviolet Photodissociation

2018 Analytical Chemistry
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MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

2018 bioRxiv
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Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations

2017 Science Advances
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The novel isotopically coded short-range photo-reactive crosslinker 2,4,6-triazido-1,3,5-triazine (TATA) for studying protein structures.

2016 Journal of Proteomics
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Isotopically-coded short-range hetero-bifunctional photo-reactive crosslinkers for studying protein structure.

2015 Journal of Proteomics
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14N15N DXMSMS Match program for the automated analysis of LC/ESI-MS/MS crosslinking data from experiments using 15N metabolically labeled proteins

2014 Journal of Proteomics
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Citations (18)