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Joanna P. Davies

Icahn School of Medicine at Mount Sinai

23

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2307

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MLN64 Transport to the Late Endosome Is Regulated by Binding to 14-3-3 via a Non-canonical Binding Site

2012 PLOS ONE
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Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent.

2009 Journal of Lipid Research
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Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8

2009 Journal of Lipid Research
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Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1 / mice

2008 American Journal of Physiology-gastrointestinal and Liver Physiology
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Niemann-Pick C1-Like 1 Is Required for an LXR Agonist to Raise Plasma HDL Cholesterol in Mice

2008 Arteriosclerosis, Thrombosis, and Vascular Biology
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Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane

2007 Biochimica et Biophysica Acta
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Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.

2007 Biochimica et Biophysica Acta
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Endosomal Accumulation of Toll-Like Receptor 4 Causes Constitutive Secretion of Cytokines and Activation of Signal Transducers and Activators of Transcription in Niemann–Pick Disease Type C (NPC) Fibroblasts: A Potential Basis for Glial Cell Activation in the NPC Brain

2007 The Journal of Neuroscience
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Hepatic Niemann-Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

2007 Journal of Clinical Investigation
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Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4.

2006 Journal of Cell Science
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Citations (28)