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Disha Awasthy

AstraZeneca

14

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336

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Whole cell screen based identification of spiropiperidines with potent antitubercular properties

2015 Bioorganic & Medicinal Chemistry Letters
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Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target

2015 Tuberculosis
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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.

2015 Bioorganic & Medicinal Chemistry
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Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro.

2014 Gene
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Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.

2014 Journal of Medicinal Chemistry
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Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice.

2012 Microbiology
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Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis

2010 Microbiology
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Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice.

2009 Microbiology
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