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Anu Moilanen

Orion Corporation

12

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105

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Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors

2020 Cancer Research
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Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion

2016 Oncogene
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Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors.

2015 Bioorganic & Medicinal Chemistry Letters
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432 ODM-203, a novel, selective and balanced FGFR and VEGFR inhibitor with strong anti-tumor activity in FGFR- and VEGFR-dependent cancer models

2014 European Journal of Cancer
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Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.

2014 Bioorganic & Medicinal Chemistry
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Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors

2013 ACS Medicinal Chemistry Letters
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Faulty epithelial polarity genes and cancer.

2011 Advances in Cancer Research
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