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Kiyoshi Mizukami

Daiichi Sankyo

9

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Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

2014 Bioorganic & Medicinal Chemistry Letters
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Evaluation of the Therapeutic Index of a Novel Phosphodiesterase 4B–Selective Inhibitor Over Phosphodiesterase 4D in Mice

2013 Journal of Pharmacological Sciences
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Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

2013 Bioorganic & Medicinal Chemistry Letters
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The authors state no conflict of interest.

2012
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Depression by carbachol on excitatory synaptic transmission to substantia gelatinosa neuron.

1996 Japanese Journal of Pharmacology
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