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Anthony Nichols

Merck Serono

19

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2804

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Pharmacophore‐Based Design of Novel Oxadiazoles as Selective Sphingosine‐1‐phosphate (S1P) Receptor Agonists with in vivo Efficacy

2015 ChemMedChem
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Discovery of a novel series of potent S1P1 agonists.

2010 Bioorganic & Medicinal Chemistry Letters
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Cellular imaging in drug discovery

2006 Nature Reviews Drug Discovery
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Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ

2006 Journal of Medicinal Chemistry
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Discovery and Development of a New Class of Potent, Selective, Orally Active Oxytocin Receptor Antagonists

2005 Journal of Medicinal Chemistry
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The DRY motif as a molecular switch of the human oxytocin receptor

2005 Biochemistry
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Design, synthesis, and biological activity of novel, potent, and selective (Benzoylaminomethyl)thiophene sulfonamide inhibitors of c-jun-N-terminal kinase

2004 Journal of Medicinal Chemistry
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Pharmacology of (2S,4Z)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2′-methyl[1,1′-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a New Potent and Selective Nonpeptide Antagonist of the Oxytocin Receptor

2003 Journal of Pharmacology and Experimental Therapeutics
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Substrate Recognition Domains within Extracellular Signal-regulated Kinase Mediate Binding and Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase-3

2000 Journal of Biological Chemistry
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Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

1999 Journal of Cell Biology
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