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Nancy H.C. Loos
Nancy H.C. Loos
Netherlands Cancer Institute
Chemistry
Pharmacokinetics
Protein precipitation
Liquid chromatography–mass spectrometry
Selected reaction monitoring
4
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ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
2021
Pharmacological Research
Alejandra Martínez-Chávez
Nancy H.C. Loos
Maria C. Lebre
Matthijs M. Tibben
Hilde Rosing
Jos H. Beijnen
Alfred H. Schinkel
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Quantification of KRAS inhibitor sotorasib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry
2021
Journal of Chromatography A
Irene A. Retmana
Nancy H.C. Loos
Alfred H. Schinkel
Jos H. Beijnen
Rolf W. Sparidans
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Quantification of KRAS inhibitor sotorasib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry
2021
Journal of Chromatography B
Irene A. Retmana
Nancy H.C. Loos
Alfred H. Schinkel
Jos H. Beijnen
Rolf W. Sparidans
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P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib.
2021
Molecular Pharmaceutics
Margarida L F Martins
Nancy H.C. Loos
Sümeyra Mucuk
Danielle de Jong
Maria C. Lebre
Hilde Rosing
Matthijs M. Tibben
Jos H. Beijnen
Alfred H. Schinkel
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