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John Stellwagen
John Stellwagen
Research Triangle Park
Biology
MAPK/ERK pathway
Thiazole
Chemistry
Kinase
4
Papers
188
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Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors.
2013
ACS Medicinal Chemistry Letters
Tara Renae Rheault
John Stellwagen
George Adjabeng
Keith Hornberger
Kimberly G. Petrov
Alex G. Waterson
Scott Howard Dickerson
Robert A. Mook
Sylvie Laquerre
Alastair J. King
Olivia W. Rossanese
Marc R. Arnone
Kimberly N. Smitheman
Laurie S. Kane-Carson
Chao Han
Ganesh S. Moorthy
Katherine G. Moss
David E. Uehling
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Citations (120)
Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup.
2011
Bioorganic & Medicinal Chemistry Letters
John Stellwagen
George Adjabeng
Marc R. Arnone
Scott Howard Dickerson
Chao Han
Keith Hornberger
Alastair J. King
Robert A. Mook
Kimberly G. Petrov
Tara Renae Rheault
Cynthia M. Rominger
Olivia W. Rossanese
Kimberly N. Smitheman
Alex G. Waterson
David E. Uehling
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Citations (24)
Oxazole and thiazole compounds benzenesulfonamide
2009
Jerry Leroy Adams
Scott Howard Dickerson
Neil W. Johnson
Kevin Kuntz
Kimberly G. Petrov
Jeffrey M. Ralph
Tara Renae Rheault
Gregory Schaaf
John Stellwagen
Xinrong Tian
David Edward Uehling
Alex G. Waterson
Brian Wilson
George Adjabeng
Keith Hornberger
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Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B‐RafV600E mutation
2009
Molecular Cancer Therapeutics
Sylvie Laquerre
Marc R. Arnone
Katherine G. Moss
Jingsong Yang
Kelly E. Fisher
Laurie S. Kane-Carson
Kimberly N. Smitheman
Jessica Ward
Bradley Heidrich
Tara Renae Rheault
George Adjabeng
Keith Hornberger
John Stellwagen
Alex G. Waterson
Chao Han
Robert A. Mook
David E. Uehling
Alastair J. King
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Citations (44)
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