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Michael C. Linhares
Michael C. Linhares
Pfizer
Chemistry
Biochemistry
Chromatography
In vitro
Pharmacokinetics
5
Papers
214
Citations
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Discovery of potent and orally bioavailable heterocycle-based β3-adrenergic receptor agonists, potential therapeutics for the treatment of obesity
2007
Bioorganic & Medicinal Chemistry Letters
Jennifer Lafontaine
Robert Francis Day
Joe Dibrino
John R. Hadcock
Diane M. Hargrove
Michael C. Linhares
Kelly A. Martin
Tristan S. Maurer
Nancy A. Nardone
David A. Tess
Paul DaSilva-Jardine
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Citations (16)
A Novel Series of Non-Carboxylic Acid, Non-Hydantoin Inhibitors of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models: 6-(5-Chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and Congeners
2005
Journal of Medicinal Chemistry
Banavara L. Mylari
Sandra J. Armento
David A. Beebe
Edward L. Conn
James B. Coutcher
Michael S. Dina
Melissa T. Ogorman
Michael C. Linhares
William H. Martin
Peter J. Oates
David A. Tess
Gregory J. Withbroe
William James Zembrowski
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Citations (60)
A Highly Selective, Non-Hydantoin, Non-Carboxylic Acid Inhibitor of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models: 6-(5-Chloro-3-methylbenzofuran- 2-sulfonyl)-2-H-pyridazin-3-one
2003
Journal of Medicinal Chemistry
Banavara L. Mylari
Sandra J. Armento
David A. Beebe
Edward L. Conn
James B. Coutcher
Michael S. Dina
Melissa T. Ogorman
Michael C. Linhares
William H. Martin
Peter J. Oates
David A. Tess
Gregory J. Withbroe
William James Zembrowski
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Citations (58)
Influence of Microsomal Concentration on Apparent Intrinsic Clearance: Implications for Scaling in Vitro Data
2001
Drug Metabolism and Disposition
J. Cory Kalvass
David A. Tess
Craig Giragossian
Michael C. Linhares
Tristan S. Maurer
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Citations (54)
Simultaneous determination of danofloxacin and N-desmethyldanofloxacin in cattle and chicken edible tissues by liquid chromatography with fluorescence detection
1996
Journal of Chromatography B: Biomedical Sciences and Applications
Timothy J. Strelevitz
Michael C. Linhares
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Citations (26)
1