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Colin J. Loweth
Colin J. Loweth
In vivo
Biochemistry
MAP kinase kinase kinase
Kinase
Chemistry
4
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98
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Discovery, Synthesis, and Characterization of an Orally Bioavailable, Brain Penetrant Inhibitor of Mixed Lineage Kinase 3
2013
Journal of Medicinal Chemistry
Val S. Goodfellow
Colin J. Loweth
Satheesh Babu Ravula
Torsten Wiemann
Thong X. Nguyen
Yang Xu
Daniel Todd
David W. Sheppard
Scott Pollack
Oksana Polesskaya
Daniel F. Marker
Stephen Dewhurst
Harris A. Gelbard
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The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
2013
The Journal of Neuroscience
Daniel F. Marker
Marie-Ève Tremblay
Jenna M. Puccini
Justin Barbieri
Mary A. Gantz Marker
Colin J. Loweth
E. Chris Muly
Shao-Ming Lu
Val S. Goodfellow
Stephen Dewhurst
Harris A. Gelbard
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Bizyklische heteroarylkinase-hemmer und verfahren zu ihrer verwendung
2011
Harris A. Gelbard
Stephen Dewhurst
Val S. Goodfellow
Torsten Wiemann
Satheesh Babu Ravula
Colin J. Loweth
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Hétéroaryles bicycliques formant inhibiteurs de la kinase et procédés d'utilisation
2011
Harris A. Gelbard
Stephen Dewhurst
Val S. Goodfellow
Torsten Wiemann
Satheesh Babu Ravula
Colin J. Loweth
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