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Rima Rozen

Montreal Children's Hospital
McGill University
McGill University Health Centre

233

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Shifting landscapes of human MTHFR missense-variant effects.

2021 American Journal of Human Genetics
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Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Methyl Metabolism and in Sex-specific Placental Transcription Changes.

2021 Molecular Nutrition & Food Research
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A common risk variant in the MTHFR gene contributes to age‐related cerebrovascular dysfunction in VCID: Development of new models and analysis methods/novel assays and technologies

2020 Alzheimers & Dementia
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Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism.

2020 Nutrients
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Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver

2019 Molecular Nutrition & Food Research
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Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation

2018 Human Molecular Genetics
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Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.

2017 Molecular Carcinogenesis
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High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.

2017 Human Molecular Genetics
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Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development

2016 The American Journal of Clinical Nutrition
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Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5′-end methylation

2016 Mammalian Genome
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