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Qi Sun

Vanderbilt University

16

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918

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Reply to Tran et al.: Dimeric KRAS protein–protein interaction stabilizers

2020 Proceedings of the National Academy of Sciences of the United States of America
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Discovery of Potent 2-Aryl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design

2018 Journal of Medicinal Chemistry
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Ligand-bound Ras:SOS:Ras complex

2018
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Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

2018 ACS Medicinal Chemistry Letters
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High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.

2018 Analytical Biochemistry
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Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

2018 Journal of Medicinal Chemistry
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Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

2018 Journal of Medicinal Chemistry
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Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC.

2015 Molecular Cell
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Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

2014 Proceedings of the National Academy of Sciences of the United States of America
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Abstract 4417: Targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

2014 Cancer Research
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