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Valerie M. Tesmer

University of Michigan

26

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870

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TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis.

2021 JCI insight
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Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres.

2021 Nature Communications
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The clinical and functional effects of TERT variants in myelodysplastic syndrome.

2021 Blood
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Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells

2019 Cell Reports
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The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action

2018 Cell Reports
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Dissecting the telomere-inner nuclear membrane interface formed in meiosis

2017 Nature Structural & Molecular Biology
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Structure of the TRF1-TERB1 interface

2017
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Structural and functional consequences of a disease mutation in the telomere protein TPP1

2016 Proceedings of the National Academy of Sciences of the United States of America
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Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq Complex

2013 Structure
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How Gα q Regulates PIP 2 Hydrolysis: Molecular Mechanisms and Prospects for Drug Development

2012 The FASEB Journal
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