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David Alvarez-Carbonell

Case Western Reserve University

13

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The Nerve Growth Factor IB-like Receptor Nurr1 (NR4A2) recruits CoREST transcription repressor complexes to silence HIV following proviral reactivation in microglial cells

2021 bioRxiv
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Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress

2020 bioRxiv
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Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across blood-brain barrier to eradicate latent HIV-1 infection

2019 Scientific Reports
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CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells

2019 International Journal of Molecular Sciences
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Cross-talk between microglia and neurons regulates HIV latency

2019 PLOS Pathogens
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HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency

2018 Journal of NeuroVirology
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Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells

2017 Retrovirology
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A-104 Distinct mechanisms of hormonal control of HIV latency in T-cells and microglial cells

2016 Journal of Acquired Immune Deficiency Syndromes
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RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

2014 Proceedings of the National Academy of Sciences of the United States of America
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