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J. Torin Huzil

University of Alberta

17

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599

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Interactions of Laulimalide, Peloruside, and Their Derivatives with the Isoforms of β‐Tubulin

2013 ChemInform
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A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant.

2013 Molecular Pharmaceutics
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Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

2010 Chemistry & Biology
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Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach

2009 Journal of Molecular Graphics & Modelling
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Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.

2009 Journal of Chemical Information and Modeling
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Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms

2008 Journal of Chemical Information and Modeling
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A Unique Mode of Microtubule Stabilization Induced by Peloruside A

2008 Journal of Molecular Biology
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Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms.

2008 ChemInform
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Conformational Analysis of the Carboxy-Terminal Tails of Human β-Tubulin Isotypes

2008 Biophysical Journal
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The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

2006 The International Journal of Developmental Biology
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Citations (66)