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Anu Nigam
Anu Nigam
Harvard University
Medicine
Clopidogrel
Pharmacodynamics
CYP2C19
P2Y12
4
Papers
271
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Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function.
2013
Journal of the American College of Cardiology
Andrew L. Frelinger
Deepak L. Bhatt
Ronald D. Lee
Darcy Mulford
Jingtao Wu
Sai Nudurupati
Anu Nigam
Michael Lampa
Julie K. Brooks
Marc R. Barnard
Alan D. Michelson
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Citations (161)
A Randomized, 2-Period, Crossover Design Study to Assess the Effects of Dexlansoprazole, Lansoprazole, Esomeprazole, and Omeprazole on the Steady-State Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Volunteers
2012
Journal of the American College of Cardiology
Andrew L. Frelinger
Ronald D. Lee
Darcy Mulford
Jingtao Wu
Sai Nudurupati
Anu Nigam
Julie K. Brooks
Deepak L. Bhatt
Alan D. Michelson
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Citations (108)
Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function
2012
Blood
Andrew L. Frelinger
Deepak L. Bhatt
Ronald D. Lee
Darcy Mulford
Jingtao Wu
Sai Nudurupati
Anu Nigam
Michael Lampa
Julie K. Brooks
Marc R. Barnard
Alan D. Michelson
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Citations (2)
In Vivo Platelet Activation and Its In Vitro Inhibition by Prasugrel's Active Metabolite In Adolescents with Sickle Cell Disease
2011
Blood
Andrew L. Frelinger
Joseph A. Jakubowski
Julie K. Brooks
Anu Nigam
Michelle A. Berny-Lang
Marc R. Barnard
Matthew M. Heeney
Alan D. Michelson
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