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John T. Catlow

Eli Lilly and Company

31

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The α2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats

2019 Pharmacology, Biochemistry and Behavior
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Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain

2019 Journal of Pharmacology and Experimental Therapeutics
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Discovery of dual positive allosteric modulators (PAMs) of the metabotropic glutamate 2 receptor and CysLT1 antagonists for treating migraine headache

2017 Bioorganic & Medicinal Chemistry Letters
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In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu2/3 receptor antagonist.

2017 Neuropharmacology
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Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice.

2017 Cns & Neurological Disorders-drug Targets
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Comparative Effects of LY3020371, a Potent and Selective mGlu2/3 Receptor Antagonist, and Ketamine, a Non-Competitive NMDA Receptor Antagonist, in Rodents: Evidence Supporting Use for the Treatment of Depression

2017 Journal of Pharmacology and Experimental Therapeutics
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Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611)

2017 Cns & Neurological Disorders-drug Targets
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Metabotropic Glutamate Receptor

2016
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Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression

2016 Bioorganic & Medicinal Chemistry Letters
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Metabotropic Glutamate Receptor in complex with antagonist (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

2016
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