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Barbara H. Stokes

Columbia University

16

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590

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P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites

2021 bioRxiv
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Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

2021 eLife
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Mutation in Plasmodium falciparum BTB/POZ domain of K13 protein confers artemisinin resistance.

2021 Antimicrobial Agents and Chemotherapy
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Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival.

2021 Nature Communications
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The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites

2020 Chemistry & Biology
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Oligonucleotides used in this study.

2020 PLOS Pathogens
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Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13.

2020 PLOS Pathogens
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Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda.

2020 Nature Medicine
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The Antimalarial Natural Product Salinipostin a Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. Falciparum Parasites

2019
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