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Nikhil Madhusudhan
Nikhil Madhusudhan
Broad Institute
Cancer
Biology
Biochemistry
Enzyme
Glycine
4
Papers
1273
Citations
0.01
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2024
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A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins.
2020
Journal of the American Chemical Society
Panayotis C. Theodoropoulos
Wentian Wang
Albert Budhipramono
Bonne M. Thompson
Nikhil Madhusudhan
Matthew A. Mitsche
Jeffrey G. McDonald
Jef K. De Brabander
Deepak Nijhawan
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Citations (11)
Elucidating the Target and Selectivity of a Non-Small Cell Lung Cancer Toxin
2019
Nikhil Madhusudhan
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Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
2014
Nature Communications
Roland Nilsson
Mohit Jain
Nikhil Madhusudhan
Nina Gustafsson Sheppard
Laura Strittmatter
Caroline Kampf
Jenny Huang
Anna Asplund
Vamsi K. Mootha
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Citations (308)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
2012
Science
Mohit Jain
Roland Nilsson
Sonia Sharma
Nikhil Madhusudhan
Toshimori Kitami
Amanda Souza
Ran Kafri
Marc W. Kirschner
Clary B. Clish
Vamsi K. Mootha
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Citations (954)
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