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Yoram Shechter

Weizmann Institute of Science

108

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4746

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Combined local blood-brain barrier opening and systemic methotrexate for the treatment of brain tumors.

2015 Journal of Cerebral Blood Flow and Metabolism
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Angiotensin 1-7 as Means to Prevent the Metabolic Syndrome: Lessons From the Fructose-Fed Rat Model

2013 Diabetes
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Peptide derived from HIV-1 TAT protein, destabilizes a monolayer of endothelial cells in an in vitro model of the blood-brain barrier, and allows permeation of high molecular weight proteins.

2012 Journal of Biological Chemistry
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Establishing the principle of reversibility in peptide/protein and small-molecule therapy

2012 Therapeutic Delivery
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Intramolecular azo-bridge as a cystine disulfide bond surrogate: Somatostatin-14 and brain natriuretic peptide (BNP) analogs

2011 Bioorganic & Medicinal Chemistry
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Engineering prolonged-acting prodrugs employing an albumin-binding probe that undergoes slow hydrolysis at physiological conditions

2010 Journal of Controlled Release
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Citations (11)
Reversible pegylation prolongs the hypotensive effect of atrial natriuretic peptide.

2008 Bioconjugate Chemistry
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Turning low-molecular-weight drugs into prolonged acting prodrugs by reversible pegylation: a study with gentamicin.

2008 Journal of Medicinal Chemistry
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Polymyxin B and Related Cyclic Peptides Facilitate Leanness and Reduce Fat Mass and Triglyceride Content in Ageing Rats: Potential Prototype Drugs Against Obesity

2006 International Journal of Peptide Research and Therapeutics
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Oral therapy of L-glutamic acid γ-monohydroxamate-vanadium (2:1) complex: Improvement of blood glucose profile in different types of diabetic rodents

2005 Pure and Applied Chemistry
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Citations (3)