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Eleonora Adami

National University of Singapore

27

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670

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Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts

2021 Frontiers in Molecular Biosciences
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Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury

2021 Science Translational Medicine
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A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.

2021 Genome Biology
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Overturning the paradigm that IL6 signaling drives liver regrowth while shining light on a new therapeutic target for regenerative medicine

2021 bioRxiv
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IL11 is elevated in systemic sclerosis and IL11-dependent ERK signaling underlies TGFβ-mediated activation of dermal fibroblasts.

2021 Rheumatology
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IL11 in cardiac and renal fibrosis: late to the party but a central player

2020 British Journal of Pharmacology
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Citations (17)
Trans control of cardiac mRNA translation in a protein length-dependent fashion

2020 bioRxiv
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Citations (2)
Autocrine IL11 cis-signaling in hepatocytes is an initiating nexus between lipotoxicity and non-alcoholic steatohepatitis

2020 bioRxiv
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Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease

2020 The FASEB Journal
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Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Non-Alcoholic Steatohepatitis.

2019 Elements
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Citations (1)