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Ayumi Ohoka-Sugita
Ayumi Ohoka-Sugita
Taisho Pharmaceutical Co.
Chemical synthesis
Acetyl-CoA carboxylase
Biochemistry
Organic chemistry
Chemistry
3
Papers
55
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Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group.
2011
Bioorganic & Medicinal Chemistry
Tomomichi Chonan
Daisuke Wakasugi
Daisuke Yamamoto
Miyoko Yashiro
Takahiro Oi
Hiroaki Tanaka
Ayumi Ohoka-Sugita
Fusayo Io
Hiroko Koretsune
Akira Hiratate
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Citations (26)
Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors.
2010
Bioorganic & Medicinal Chemistry Letters
Tomomichi Chonan
Hiroaki Tanaka
Daisuke Yamamoto
Miyoko Yashiro
Takahiro Oi
Daisuke Wakasugi
Ayumi Ohoka-Sugita
Fusayo Io
Hiroko Koretsune
Akira Hiratate
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Citations (16)
(4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors.
2009
Bioorganic & Medicinal Chemistry Letters
Tomomichi Chonan
Takahiro Oi
Daisuke Yamamoto
Miyoko Yashiro
Daisuke Wakasugi
Hiroaki Tanaka
Ayumi Ohoka-Sugita
Fusayo Io
Hiroko Koretsune
Akira Hiratate
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Citations (13)
1