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André H.M. de Vries

DSM

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Scalable Synthesis of β-Lactamase Inhibitor QPX7728 by Sequential Nickel-Catalyzed Boron Insertion into a Benzofuran Substrate and Enantioselective Cyclopropanation of the Resulting Vinylboronate

2021 Organic Process Research & Development
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Enantioselective synthesis of a 2,3-benzodiazepine intermediate of BET inhibitor BAY 1238097 via catalytic asymmetric hydrogenation

2020 Organic Process Research & Development
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Asymmetric Synthesis of a Key Intermediate for Tofacitinib via a Dynamic Kinetic Resolution-Reductive Amination Protocol

2018 Organic Process Research & Development
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Catalytic Asymmetric Reduction of a 3,4-Dihydroisoquinoline for the Large-Scale Production of Almorexant : Hydrogenation or Transfer Hydrogenation?

2013 Organic Process Research & Development
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Asymmetric homogeneous hydrogenations at scale

2012 Chemical Society Reviews
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Asymmetric Synthesis of (S)-2-Indolinecarboxylic Acid by Combining Biocatalysis and Homogeneous Catalysis

2011 Chemcatchem
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Asymmetric Hydrogenation of a 2-Isopropylcinnamic Acid Derivative en route to the Blood Pressure-Lowering Agent Aliskiren

2011 ChemInform
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Sustainable route design for pharmaceuticals why, how and when

2010 Chimica Oggi-chemistry Today
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Under Pressure: Rapid Development of Scalable Asymmetric Hydrogenation Catalysts

2010 Topics in Catalysis
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Efficient preparation of an N-aryl β-amino acid via asymmetric hydrogenation and direct asymmetric reductive amination en route to Ezetimibe

2010 Tetrahedron-asymmetry
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Citations (35)