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Jian Xu

University of Southern California

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Cellular pathways influenced by protein arginine methylation: Implications for cancer

2021 Molecular Cell
- Jian Xu
- Stéphane Richard
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Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling.

2021 Journal of Biological Chemistry
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Arginine methylation in the epithelial-to-mesenchymal transition.

2021 FEBS Journal
- Jian Qin
- Jian Xu
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Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors.

2021 Cell Reports
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Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes.

2020 Genes & Development
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Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription.

2020 Neoplasia
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Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

2019 Nature Communications
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Deep protein methylation profiling by combined chemical and immunoaffinity approaches reveals novel PRMT1 targets

2019 Molecular & Cellular Proteomics
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Deep protein methylation profiling by combined chemical and immunoaffinity approaches reveals novel PRMT1 targets

2019 bioRxiv
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Smad6 Methylation Represses NFκB Activation and Periodontal Inflammation

2018 Journal of Dental Research
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